研究队伍
 
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研究队伍

姓 名:
  粟武
性 别:
  男
职 称:
  研究员
学 历:
  博士
通讯地址:
  广东省深圳市南山区西丽深圳大学城学苑大道1068号
电 话:
  0755-86585203
传 真:
 
电子邮件:
  wu.su@siat.ac.cn
个人主页:
 

简介:

粟武,博士,研究员,博士生导师。2007年在德国Max-Planck 研究所以及Tuebingen大学化学和药学院联合培养获得博士学位。2008-2011年间在英国莱斯特大学化学系化学生物学中心留学工作。2011年任中国科学院深圳先进技术研究院研究员。2013年获得中国科学院“百人计划”A类择优资助,并入选深圳市海外高层次人才“孔雀人才”B类。


研究方向:

1)多肽药物设计和合成

2)大分子药物的缓控释放和靶向给药

 


专家类别:

职务:
所长助理

社会任职:

获奖及荣誉:

中国科学院“百人计划”,深圳市海外高层次人才“孔雀人才”B类

代表论著:

  

1. Chunlei Wu#, Zhengyin Pan#, Guiyang Yao, Wei Wang, Lijing Fang*, Wu Su*. Synthesis and structure-activity relationship studies of teixobactin analogues. RSC Advances, 2017, 7, 1923-1926.

2. Xihong Liu, Yijie Wang, Dongxu Yang, Jinlong Zhang, Dongsheng Liu* and Wu Su*. Catalytic asymmetric inverse-electron-demand 1, 3-depolar cycloaddition of C, N-cyclic azomethine imines with azlactones: an easy access to chiral tricyclic tetrahydroisoquinolines. Angew. Chem. Int. Ed., 2016, 55, 8100-8103.

3. Liang Huang#, Lijiao Ao#, Dehong Hu#, Wei Wang, Zonghai Sheng, and Wu Su*, Magneto-Plasmonic Nanocapsules for Multimodal-Imaging and Magnetically Guided Combination Cancer Therapy, Chem. Mater., 2016, 28 (16), 5896–5904.

4. Lijiao Ao, Liang Huang and Wu Su*, Composite magnetic nanocarriers for MRI and targeted drug delivery. Nanomedicine: Nanotechnology, Biology and Medicine, 2016, 12(2), 490-491.

5. Guiyang Yao#, Zhengyin Pan#, Chunlei Wu, Wei Wang, Lijing Fang*, Wu Su*. Efficient synthesis and stereochemical revision of coibamide A, J. Am. Chem. Soc., 2015, 137, 13488-13491.

6. Lijing Fang, Guiyang Yao, Zhengyin Pan, Chunlei Wu, Heng-Shan Wang, Glenn A. Burley, Wu Su*. Fully automated synthesis of DNA-binding Py-Im polyamides using a triphosgene coupling strategy. Org. Lett., 2015, 17, 158-161. 

7. Liang Huang#, Lijiao Ao#, Wei Wang, Dehong Hu, Zonghai Sheng and Wu Su*, Multifunctional magnetic silica nanotubes for MR imaging and targeted drug delivery. Chem. Commun., 2015, 51, 3923-3926.

8. Liang Huang,  Lijiao Ao, Xiaobin Xie,  Guanhui Gao,  Mohamed F. Foda  and  Wu Su*, Iron oxide nanoparticle layer templated by polydopamine spheres: a novel scaffold toward hollow–mesoporous magnetic nanoreactors, Nanoscale, 2015,7(2), 806-813.

9. Lijing Fang, Zhengyin Pan, Paul M. Cullis, Glenn A. Burley, Wu Su, UNIT 8.11 Pyrrole-Imidazole Polyamides: Automated Solid-Phase Synthesis, Current Protocols in Nucleic Acid Chemistry, 2015, 63, 8.11.1-14.

10. Lijiao Ao, Bi Wang, Peng Liu, Liang Huang, Caixia Yue, Duyang Gao, Chunlei Wu and Wu Su*, A folate-integrated magnetic polymer micelle for MRI and dual targeted drug delivery, Nanoscale, 2014, 6, 10710-10716.

11. Lijing Fang, Chunlei Wu, Zaidan Yu, Peng Shang, Yongxian Cheng, Yuefeng Peng*, and Wu Su*, Triphosgene-Mediated Couplings in the Solid Phase: Total Synthesis of Brachystemin A, Eur. J. Org. Chem., 2014, 7572–7576.

12. Wu Su, Clive R. Bagshaw, Glenn A. Burley*, Addressable and unidirectional energy transfer along a DNA three-way junction programmed by pyrrole-imidazole polyamides, Scientific Reports, 2013, 3, 1883, DOI: 10.1038/srep01883

13. Željka Krpetić, Ishwar Singh, Wu Su, Luca Guerrini, Karen Faulds, Glenn A. Burley* and Duncan Graham*, Directed Assembly of DNA-Functionalized Gold Nanoparticles Using Pyrrole–Imidazole Polyamides, J. Am. Chem. Soc., 2012, 134 (20), 8356–8359

14. Wu Su, Markus Schuster, Clive R. Bagshaw, Ulrich Rant* and Glenn A. Burley*. Site-specific assembly of DNA-based photonic wire using programmable polyamides. Angew. Chem. Int. Ed., 2011, 50, 2712-2715.

15. Wu Su, Vanessa Bonnard, Glenn A. Burley*. DNA-templated photonic arrays and assemblies: Design principles and future opportunities. Chem. Eur. J., 2011, 18, 7982-7991

16. Wu Su, Stephen J. Gray, Ruggero Dondi, and Glenn A. Burley*. Highly Efficient Synthesis of DNA-Binding Hairpin Polyamides via the Use of a New Triphosgene Coupling Strategy, Organic Letters, 2009, 11, 3910-3913.

W. Su, R. Mishra, J. Pfeuffer, K.-H. Wiesmüller, K. Ugurbil, J. Engelmann*. Synthesis and Cellular Uptake of a MR Contrast Agent Coupled to an Antisense Peptide Nucleic Acid–Cell Penetrating Peptide Conjugate. Contrast Media & Molecular Imaging, 2007, 2, 42-49.